Cover Features

2019, 31 (17)

2015, 27 (44)

 Publications

(* corresponding author; # equal contribution)

56. Quanyin Hu, Wujin Sun, Jinqiang Wang, Huitong Ruan, Xudong Zhang, Yanqi Ye, Song Shen, Chao Wang, Weiyue Lu, Ke Cheng, Gianpietro Dotti, Joshua F. Zeidner, Jun Wang, Zhen Gu*. "Conjugation of Haematopoietic Stem Cells and Platelets Decorated with Anti-PD-1 Antibodies Augments Anti-Leukaemia Efficacy". Nature Biomedical Engineering, 2, 2018.

 

55. Huitong Ruan#, Quanyin Hu#, Di Wen, Qian Chen, Guojun Chen, Yifei Lu, Jinqiang Wang, Hao Cheng, Weiyue Lu*, Zhen Gu*. “A Dual-Bioresponsive Drug Delivery Depot for Immune Checkpoint Blockade”. Advanced Materials, 31, 2019. Front Cover Featured.

 

54. Quanyin Hu, Wujin Sun, Chenggen Qian, Hunter Bomba, Hongliang Xin , Zhen Gu*. “Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy”. Advanced Materials, 29, 2017.

 

53. Quanyin Hu, Chenggen Qian, Wujin Sun, Jinqiang Wang, Zhaowei Chen, Hunter Bomba, Hongliang Xin, Qundong Shen, Zhen Gu*. “Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus”. Advanced Materials, 28, 2016.

 

52. Quanyin Hu, Wujin Sun, Yue Lu, Hunter Bomba, Yanqi Ye, Tianyue Jiang, Ari Isaacson, Zhen Gu*. “Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots”. Nano Letters, 16, 2016.

 

51. Quanyin Hu, Wujin Sun, Chenggen Qian, Chao Wang, Hunter Bomba, Zhen Gu*. “Anticancer Platelet-Mimicking Nanovehicles”. Advanced Materials, 27, 2015. Cover Featured.

 

50. Zhaowei Chen#, Quanyin Hu#, Zhen Gu*. “Leverage Engineering of Cells for Drug Delivery”. Accounts of Chemical Research, 51, 2018.

 

49. Quanyin Hu, Wujin Sun, Chao Wang, Zhen Gu*. “Recent Advances of Cocktail Chemotherapy by Combination Drug Delivery Systems”. Advanced Drug Delivery Reviews, 98, 2016.

 

48. Quanyin Hu, Qian Chen, Zhen Gu*. “Advances in Transformable Drug Delivery Systems”. Biomaterials, 178, 546-558, 2018.

 

47. Quanyin Hu, Hunter N Bomba, Zhen Gu*. “Engineering Platelet-Mimicking Drug Delivery Vehicles”. Frontiers of Chemical Science and Engineering, 4, 2017.

 

46. Quanyin Hu, Prateek Katti, Zhen Gu*. “Enzyme-Responsive Nanomaterials for Controlled Drug Delivery”. Nanoscale, 6, 2014.

 

45. Quanyin Hu, Ting Kang, Jingxian Feng, Qianqian Zhu, Tianze Jiang, Jianhui Yao, Xinguo Jiang, Jun Chen*. “Tumor Microenvironment and Angiogenic Blood Vessels Dual-Targeting for Enhanced Anti-Glioma Therapy”. ACS Applied Materials & Interfaces, 8, 2016.

 

44. Quanyin Hu, Guangzhi Gu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Yifan Tu, Zhiqing Pang, Qingxiang Song, Lei Yao, Huiming Xia, Hongzhuang Chen, Xingguo Jiang, Xiaoling Gao*, Jun Chen*. “F3 Peptide-Functionalized PEG-PLA Nanoparticles Co-Administrated with tLyp-1 Peptide for Anti-Glioma Drug Delivery”. Biomaterials, 34, 2013.

 

43. Guangzhi Gu#, Quanyin Hu#, Xinye Feng, Xiaoling Gao, Menglin Jiang, Ting Kang, Di Jiang, Qingxiang Song, Hongzhuan Chen, Jun Chen*, “PEG-PLA Nanoparticles Modified with APTEDB Peptide for Enhanced Anti-Angiogenic and Anti-Glioma Therapy”. Biomaterials, 35, 2014.

 

42. Quanyin Hu, Xiaoling Gao, Ting Kang, Xinye Feng, Di Jiang, Yifan Tu, Qingxiang Song, Lei Yao, Xinguo Jiang, Hongzhuan Chen, Jun Chen*. “CGKRK-Modified Nanoparticles for Dual-Targeting Drug Delivery to Tumor Cells and Angiogenic Blood Vessels”. Biomaterials, 34, 2013.

 

41. Quanyin Hu, Xiaoling Gao, Guangzhi Gu, Ting Kang, Yifan Tu, Zhongyang Liu, Qingxiang Song, Lei Yao, Zhiqing Pang, Xinguo Jiang, Hongzhuan Chen, Jun Chen*. “Glioma Therapy Using Tumor Homing and Penetrating Peptide-Functionalized PEG-PLA Nanoparticles Loaded with Paclitaxel”. Biomaterials, 34, 2013.

40. Jihyeon Yeom, Pedro Guimaraes, Hyomin Ahn, Bo‐Kyeong Jung, Quanyin Hu, Kevin McHugh, Michael Mitchell, Chae-Ok Yun, Robert Langer*, Ana Jaklenec*. “Chiral Engineering of Supraparticles for Controllable Nanomedicine”. Advanced Materials, 32, 2020.

 

39. Guang Yang, Qian Chen, Di Wen, Zhaowei Chen, Jinqiang Wang, Guojun Chen, Zejun Wang, Xudong Zhang, Yuqi Zhang, Quanyin Hu, Liang Zhang*, Zhen Gu*. “A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth”. ACS Nano, 13, 2019.

 

38. Qian Chen, Quanyin Hu, Elena Dukhovlinova, Guojun Chen, Sarah Ahn, Chao Wang, Edikan A. Ogunnaike, Frances S. Ligler, Gianpietro Dotti*, Zhen Gu*. “Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells”. Advanced Materials, 31, 2019.

 

37. Huitong Ruan, Linlin Bu, Quanyin Hu, Hao Cheng, Weiyue Lu*, Zhen Gu*. “Strategies of Combination Drug Delivery for Immune Checkpoint Blockades”. Advanced Healthcare Materials, 8, 2019.

 

36. Qian Chen, Chao Wang, Xudong Zhang, Guojun Chen, Quanyin Hu, Hongjun Li, Jinqiang Wang, Di Wen, Yuqi Zhang, Yifei Lu, Guang Yang, Chen Jiang, Jun Wang, Gianpietro Dotti, Zhen Gu*. “In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment”. Nature Nanotechnology, 14, 2019.

 

35. Yifei Lu, Quanyin Hu, Chen Jiang*, Zhen Gu*. “Platelet for Drug Delivery”. Current Opinion Biotechnology, 58, 2018.

 

34. Xudong Zhang, Jinqiang Wang, Zhaowei Chen, Quanyin Hu, Chao Wang, Junjie Yan, Gianpietro Dotti, Peng Huang*, Zhen Gu*. “Engineering PD-1-Presenting Platelets for Cancer Immunotherapy”. Nano Letters, 18, 2018.

 

33. Qian Chen, Chao Wang, Guojun Chen, Quanyin Hu, Zhen Gu*. “Delivery Strategies for Immune Checkpoint Blockade”. Advanced Healthcare Materials, 7, 2018.

 

32. Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*. “Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade”. Advanced Materials, 30, 2018.

 

31. Xudong Zhang, Chao Wang, Jinqiang Wang, Quanyin Hu, Benjamin Langworthy, Yanqi Ye, Wujin Sun, Jing Lin, Tianfu Wang, Jason Fine, Hao Cheng, Gianpietro Dotti, Peng Huang*, Zhen Gu*. “PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy”. Advanced Materials, 30, 2018.

 

30. Chao Wang, Jinqiang Wang, Xudong Zhang, Shuangjiang Yu, Di Wen, Quanyin Hu, Yanqi Ye, Hunter Bomba, Xiuli Hu, Zhuang Liu, Gianpietro Dotti, Zhen Gu*, “In situ Formed Reactive Oxygen Species-Responsive Scaffold with Gemcitabine and Checkpoint Inhibitor for Combination Therapy”. Science Translational Medicine, 10, 2018.

 

29. Yanqi Ye, Chao Wang, Xudong Zhang, Quanyin Hu, Yuqi Zhang, Qi Liu, Di Wen, Joshua Milligan, Adriano Bellotti, Leaf Huang, Gianpietro Dotti, Zhen Gu*. “A Melanin-Mediated Cancer Immunotherapy Patch”. Science Immunology, 2, 2017.

 

28. Chao Wang, Yanqi Ye, Quanyin Hu, Adriano Bellotti, Zhen Gu*. “Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook”. Advanced Materials, 29, 2017.

 

27. Yue Lu, Yiliang Lin, Zhaowei Chen, Quanyin Hu, Yang Liu, Shuangjiang Yu, Wei Gao, Michael Dickey, Zhen Gu*. “Enhanced Endosomal Escape by Light-Fueled Liquid-Metal Transformer”. Nano Letters, 17, 2017.

 

26. Chenggen Qian, Peijian Feng, Jicheng Yu, Yulei Chen, Quanyin Hu, Wujin Sun, Xuanzhong Xiao, Xiuli Hu, Adriano Bellotti, Qundong Shen, Zhen Gu*. “Anaerobe-Inspired Anticancer Nanovesicles”. Angew Chem Int Ed Engl, 56, 2017.

 

25. Lingyan Lv, Yan Jiang, Xin Liu, Baoyan Wang, Wei Lv, Yue Zhao, Huihui Shi, Quanyin Hu, Hongliang Xin*, Qunwei Xu*, Zhen Gu. “Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles”. Molecular Pharmaceutics, 13, 2016.

 

24. Yanqi Ye, Jinqiang Wang, Quanyin Hu, Gabriella Hochu, Hongliang Xin, Chao Wang, Zhen Gu*. “Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors”. ACS Nano, 10, 2016.

 

23. Chenggen Qian, Yulei Chen, Sha Zhu, Jicheng Yu, Lei Zhang, Peijian Feng, Xin Tang, Quanyin Hu, Wujin Sun, Yue Lu, Xuanzhong Xiao, Qundong Shen,and Zhen Gu*. “ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging”. Theranostics, 6, 2016.

 

22. Yue Zhao, Yan Jiang, Wei Lv, Zhongyuan Wang, Lingyan Lv, Baoyan Wang, Xin Liu, Yang Liu, Quanyin Hu, Wujin Sun, Qunwei Xu, Hongliang Xin*, Zhen Gu. “Dual Targeted Nanocarrier for Brain Ischemic Stroke Treatment.” Journal of Controlled Release, 10, 2016.

 

21. Wujin Sun, Wenyan Ji, Quanyin Hu, Jicheng Yu, Chao Wang, Chenggen Qian, Gabrielle Hochu, Zhen Gu*. “Transformable DNA nanocarriers for Plasma Membrane Targeted Delivery of Cytokine”. Biomaterials, 96, 2016.

 

20. Chenggen Qian, Jicheng Yu, Yulei Chen, Quanyin Hu, Xuanzhong Xiao, Wujin Sun, Chao Wang, Peijian Feng, Quandong Shen, Zhen Gu*. “Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy”. Advanced Materials, 28, 2016.

 

19. Dongquan Shi, Xingquan Xu, Yanqi Ye, Kai Song, Yixiang Cheng, Jin Di, Quanyin Hu, Jianxin Li, Huangxian Ju, Qing Jiang*, Zhen Gu*. “Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration”. ACS Nano, 10, 2016.

 

18. Yue Lu, Quanyin Hu, Yiliang Lin, Dennis Pacardo, Chao Wang, Wujin Sun, Frances Ligler, Michael Dickey, Zhen Gu*. “Transformable Liquid-Metal Nanomedicine”. Nature Communications, 6, 2015.

 

17. Wujin Sun, Wenyan Ji, Jordan Hall, Quanyin Hu, Chao Wang, Chase Beisel, Zhen Gu*. “Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing”. Angew Chem Int Ed Engl, 54, 2015.

 

16. Jin Di, Jinwook Kim, Quanyin Hu, Xiaoning Jiang*, Zhen Gu*. “Spatiotemporal Drug Delivery Using Laser-Generated-Focused Ultrasound System”. Journal of Controlled Release, 220, 2015.

 

15. Ting Kang, Xiaoling Gao, Quanyin Hu, Di Jiang, Xinye Feng, Xue Zhang, Qingxiang Song, Lei Yao, Meng Huang, Xinguo Jiang, Zhiqing Pang, Hongzhuang Chen, Jun Chen*. “iNGR-Modified PEG-PLGA Nanoparticles That Recognize Tumor Vasculature and Penetrate Gliomas”. Biomaterials, 35, 2014.

 

14. Qingxiang Song, Meng Huang, Lei Yao, Xiaolin Wang, Xiao Gu, Juan Chen, Jun Chen, Jialin Huang, Quanyin Hu, Ting Kang, Zhengxing Rong, Hong Qi, Gang Zheng*, Hongzhuan Chen*, Xiaoling Gao*. “Lipoprotein-Based Nanoparticles Rescue the Memory Loss of Mice with Alzheimer’s Disease by Accelerating the Clearance of Amyloid-Beta”. ACS Nano, 8, 2014.

 

13. Lei Yao, Qingxiang Song, Wenkun Bai, Jizhen Zhang, Deyu Miao, Mengyin Jiang, Yu Wang, Zhiyong Shen, Quanyin Hu, Xiao Gu, Meng Huang, Gang Zheng, Xiaoling Gao,*, Bing Hu*, Jun Chen*, Hongzhuan Chen*. “Facilitated Brain Delivery of Poly (Ethylene Glycol)-Poly (Lactic Acid) Nanoparticles by Microbubble-Enhanced Unfocused Ultrasound”. Biomaterials, 35, 2014.

 

12. Deyu Miao, Mengyin Jiang, Zhongyang Liu, Guangzhi Gu, Quanyin Hu, Ting Kang, Qingxiang Song, Lei Yao, Wei Li, Xiaoling Gao*, Mingjiang Sun, Jun Chen*. “Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy”. Molecular Pharmaceutics, 11, 2014.

 

11. Zhongyang Liu, Xiaoling Gao, Ting Kang, Mengyin Jiang, Deyu Miao, Guangzhi Gu, Quanyin Hu, Qingxiang Song, Lei Yao, Yifan Tu, Hongzhuan Chen, Xinguo Jiang, and Jun Chen*. “B6 Peptide-Modified PEG-PLA Nanoparticles for Enhanced Brain Delivery of Neuroprotective Peptide”. Bioconjugate Chemistry, 24, 2103.

 

10. Guangzhi Gu, Xiaoling Gao, Quanyin Hu, Ting Kang, Zhongyang Liu, Mengyin Jiang, Deyu Miao, Qingxiang Song, Lei Yao, Yifan Tu, Zhiqing Pang, Hongzhuan Chen, Xinguo Jiang, Jun Chen*. “The Influence of the Penetrating Peptide iRGD on the Effect of Paclitaxel-Loaded MT1-AF7p-Conjugated Nanoparticles on Glioma Cells”. Biomaterials, 34, 2013.

 

9. Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Guangzhi Gu, Qingxiang Song, Lei Yao, Quanyin Hu, Yifan Tu, Zhiqing Pang, Hongzhuan Chen, Xinguo Jiang, Xiaoling Gao, Jun Chen*. “Lactoferrin-Modified PEG-co-PCL Nanoparticles for Enhanced Brain Delivery Of NAP Peptide Following Intranasal Administration”. Biomaterials, 34, 2013.

 

8. Qingxiang Song, Xiaolin Wang, Quanyin Hu, Meng Huang, Lei Yao, Hong Qi, Yu Qiu, Xinguo Jiang, Jun Chen, Hongzhuan Chen, Xiaoling Gao*. “Cellular Internalization Pathway and Transcellular Transport of Pegylated Polyester Nanoparticles in Caco-2 Cells”. International Journal of Pharmaceutics, 445, 2013.

 

7. Huimin Xia, Guangzhi Gu, Quanyin Hu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Qingxiang Song, Lei Yao, Yifan Tu, Hongzhuan Chen, Xiaoling Gao*, and Jun Chen*. “Activatable Cell Penetrating Peptide-Conjugated Nanoparticles with Enhanced Permeability for Site-Specific Targeting Delivery of Anticancer Drug”. Bioconjugate Chemistry, 24, 2013.

 

6. Guangzhi Gu, Huimin Xia, Quanyin Hu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Yifan Tu, Zhiqing Pang, Qingxiang Song, Lei Yao, Hongzhan Chen, Xiaoling Gao*, Jun Chen*. “PEG-co-PCL Nanoparticles Modified with MMP-2/9 Activatable Low Molecular Weight Protamine for Enhanced Targeted Glioblastoma Therapy”. Biomaterials, 34, 2013.

 

5. Ni Zeng, Xiaoling Gao, Quanyin Hu, Qingxiang Song, Huimin Xia, Zhongyang Liu, Guangzhi Gu, Mengyin Jiang, Zhiqing Pang, Hongzhuan Chen, Jun Chen, Liang Fang*. “Lipid-based Liquid Crystalline Nanoparticles as Oral Drug Delivery Vehicles for Poorly Water-Soluble Drugs: Cellular Interaction and In Vivo Absorption”. International Journal of Nanomedicine, 7, 2012.

 

4. Huimin Xia, Xiaoling Gao, Guangzhi Gu, Zhongyang Liu, Quanyin Hu, Yifan Tu, Qingxiang Song, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chena, Hongzhuan Chen*. “Penetratin-Functionalized PEG-PLA Nanoparticles for Brain Drug Delivery”. International Journal of Pharmaceutics, 436, 2012.

 

3. Qingxiang Song, Lei Yao, Meng Huang, Quanyin Hu, Qin Lu, Bingxian Wu, Hong Qi, Zhengxing Rong, Xinguo Jiang, Xiaoling Gao*, Jun Chen*, Hongzhuan Chen*. “Mechanisms of Transcellular Transport of Wheat Germ Agglutinin-Functionalized Polymeric Nanoparticles in Caco-2 Cells”. Biomaterials, 33, 2012.

 

2. Ni Zeng, Quanyin Hu, Zhongyang Liu, Xiaoling Gao, Rongkuan Hu, Qingxiang Song, Guangzhi Gu, Huimin Xia, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chen, Liang Fang*. “Preparation and Characterization of Paclitaxel-Loaded DSPE-PEG-Liquid Crystalline Nanoparticles (LCNPs) for Improved Bioavailability”. International Journal of Pharmaceutics, 424, 2012.

 

1. Huimin Xia, Xiaoling Gao, Guangzhi Gu, Zhongyang Liu, Ni Zeng, Quanyin Hu, Qingxiang Song, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chen*, Hongzhuan Chen*, “Low molecular weight protamine-functionalized nanoparticles for drug delivery to the brain after intranasal administration”. Biomaterials, 32, 2011.

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